基因 PCR Array在免疫炎症研究中的应用( 二 ) 新型冠状肺炎

B cellsDifferentiation induces acute phase proteinsIL-12T cellsNK cellsActivates NK cells

Tumour necrosis factors
Cytokine	Main sources	Target cell	Major function
TNF-α	Macrophages	Macrophages	Phagocyte cell activation endotoxic shock
Monocytes	Tumour cells	Tumour cytotoxicity cachexia
TNF-β	T-cells	Phagocytes tumour cells	Chemotactic phagocytosis oncostatic induces other cytokines

Interferons
Cytokine	Main sources	Target cell	Major function
IFN-α	Leukocytes	Various	Anti-viral
IFN-β	Fibroblasts	Various	Anti-viral anti-proliferative
IFN-γ	T-cells	Various	Anti-viral macrophage activation increases neutrophil and monocyte function MHC-I and -II expression on cells

Colony stimulating factors
Cytokine	Main sources	Target cell	Major function
G-CSF	Fibroblasts endothelium	Stem cells in BM	Granulocyte production
GM-CSF	T cells macrophages fibroblasts	Stem cells	Granulocyte monocyte eosinophil production
M-CSF	Fibroblast endothelium	Stem cells	Monocyte production and activation
Erythropoietin	Endothelium	Stem cells	Red blood cell production